Cirno's Medi-Beam

Can be skipped, sell at late-game for better items.

Buy early and build stacks with assists, sell at late-game for better items. Can be replaced by other 1.6k greens if you don't like it or the matchup doesn't favor this item.

Can be sold late-game for better items

Boosts all of your heal by a decent margin

Imbue on Ice Path so it'll be available sooner and enhance your tempo, a stepping stone to Superior Cooldown

Gives you some lee way on the tanky department.

Let your beam out-damage enemy's lifesteal or heal, also gives heal on kills and assists.

If your lane have spirit nukers, this will help you ease off some of their pressure

Highly recommended, allows you to save teammates who stepped into the deathball quicksand

If your team tend to deathball alot this can be a great option

Need a quick slack and some move speed?

Should be considered late-game or when debuffs start to go out of control.

Lets you run faster and resisting slow.

The main course and biggest beam power spike. They no longer see you as a problem, they see you as a real THREAT.

Reduces all your abilities' cooldown for better uptime which also means better tempo

The appetizing boost before your real massive power spike

For larger dome and longer beam

Gives you 2 extra healnades

Buy this when enemy team have strong gunners such as Venator, Silver, etc. This will discourage them from shooting at you

Against a spirit heavy team comp you might want a bit more armor

Enemy team have too many debuffs? This will at least help you breathe better

If enemy team has a ton of burst spirit damage or predictable CC like Lash, this can be really useful

Should only be considered after getting EE and comfortably Boundless or Infuser, by then your beam should deal enough damage to proc this item easily

Gain big heals and slight power boost

Reduces all your abilities AND items' cooldown, consider this when you're slot locked

This goes crazy against spirit teams where you can take full advantage of this

Extends duration for dome, beam and items

Extremely situational, buy only if you think another dome is worth it over other 6k

Boosts move speed and fire rate for you and teammates by popping a nade on your feet

Good Mystic Slow's sidegrade, helps keep enemies with insane mobile abilities at bay

Big AOE for fighting at urn areas

Buy this to keep ability spammer down a tad or to proc enemy's Indomitable.

Main way to disable flyers such as Vindicta, Gray Talon, Seven's Ult and Bebop's Ult. Can also be bought to stop hyper mobile heroes like Lash.

More situational, buy this if the enemy team have high HP damage sponge heroes (Mo & Krill, Abrams, etc)

You can use this to warp yourself out of dome mid-casting, trapping enemies inside while you escape elsewhere

If there're huge chunky gun damage, this is a good choice

This one spirit guy kept nuking your HP bar?

Bullet hell and gun debuffers really grind your gear?

This might help tremendously if you're facing against a CC team

If there're too many hand-held miniguns in the room.